| Summary: | 碩士 === 國防醫學院 === 病理及寄生蟲學研究所 === 107 === Abstract
Background/Aims: Diabetic distal symmetric sensory polyneuropathy (DSP) approximately accounts for 20-30% patients with type 2 diabetes in Taiwan. While the etiology of DSP in diabetes is not well understood, symptomatic treatment using pharmacological therapies is often less effective. Non-invasive, non-pharmacological therapy of high-frequency external muscle stimulation (hfEMS) has been proved as a useful tool for management of DSP in Caucasian diabetic patients. However, it is still unknown in Asian population. We designed a study to evaluate the efficacy of hfEMS for symptomatic peripheral neuropathy in patients with type 2 diabetes in Taiwan.
Materials and methods: Thirty adult patients with type 2 diabetes complicated with DSP and symptom questionnaire of pain or numbness more than score 4(score range from 1 to 10) were enrolled. Each patient received an hfEMS device (HITOP 191, gbo-Medizintechnik AG, Rimbach/Germany) for 60 min twice per week for 12 weeks. Symptom questionnaires were evaluated at baseline, 6-week and 12-week. Blood metabolic parameters were also determined.
Results: 11 male and 19 female with mean age of 65.7 years were recruited. After 12-week treatment, the symptoms of formication, burning, pain and numbness sensations of low limbs were significantly alleviated (all P<0.05). Disturbance of sleep and muscle cramp pain were also improved (P<0.001). However, body weight and blood metabolic parameters including fasting glucose, A1c, lipid profiles were not significantly changed.
Conclusion: Non-invasive hfEMS may provide a useful tool for ameliorating the neuropathic symptoms in patients with type 2 diabetes in Asian population.
|
|---|
