| Summary: | 碩士 === 逢甲大學 === 生醫資訊暨生醫工程碩士學位學程 === 107 === In many studies of Resting State Functional Magnetic Resonance Imaging (RS-fMRI), it has been shown that neurons in the human brain have spontaneous activity in the resting state and produce signals of low frequency response. Some spontaneous physiological state changes in the resting state are considered to be reflected in the signal changes of the resting state functional magnetic resonance imaging. Blood Oxygenation Level-Dependent (BOLD) is a measure of the change in oxygen content in the blood vessels of the brain caused by neuronal activity. Related studies have found that the BOLD signal obtained by functional magnetic resonance imaging has been It has been shown to change due to differences in the concentration of carbon dioxide (CO2) in the blood.
In this study, we used a gas with different concentrations of carbon dioxide to cause changes in the concentration of carbonic acid in the blood, to observe changes in the connected network of the brain at rest, and to use the volume change and graphical theory for correlation analysis.
Studies have shown that some connected networks in the brain are associated with physiological responses to changes in the concentration of carbonic acid in the blood, such as areas associated with pain perception that have significant changes in response volume and network performance.
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