The Study on The Surface Modification Parameters of Low-Temperature Atmospheric Plasma and Application on The Bacterial Anti-Adhesion

• Main Authors: Ming-Kuan Chen, 陳名冠
• Other Authors: Ming-Chen Wang
• Format: Others
• Language: zh-TW
• Published: 2019
• Online Access: http://ndltd.ncl.edu.tw/handle/3635sc

碩士 === 中原大學 === 生物醫學工程研究所 === 107 === According to World Health Organization report, nosocomial infection is the main cause of death and disability. The infection rate ranges from 5% to 10%. The cause of the infection may come from the contact of the hand to the medical equipment or environmental pollution during medical treatment, nursing and prevention. Although there is a set of management and prevention methods to prevent the infection, there are still insufficient. At the present of surface modification method, atmospheric plasma has been used widely in modification on the material surface while still maintaining its properties. Therefore, in order to construct a set of modification parameters suitable for different materials using the new atmospheric plasma equipment, a series of test comprising scanning speed test, temperature test and species test of the equipment are carried out. Then, the established data for the surface modification can be used in the future without damaging the characteristics of the materials. The study will analyze the affect of atmospheric plasma on the surface modification of glass and stainless steel (304) under different parameters. As the results from the scanning speed test, it showed that the scanning speed of the plasma equipment can affect the degree of density and modification time; the temperature test showed the highest temperature can be achieved is 84.7°C and doesn’t cause any heat damage to the surface, using X=90 mm/s, Y=5 mm/s, D=10 mm, P=0.1 MPa and Power=1000 W parameters; OES detection showed various peak atomic and molecular state of nitrogen existed in the wavelength of 315.36 nm, 336.44 nm and 357.22 nm; OH species existed in 297.62nm; and O existed in 777.32 nm, 845.75 nm and 927.28 nm; the contact angle for the glass and stainless steel to achieved hydrophobic property is above 95° from the measurement. AFM surface analysis showed that the surface roughness of the modified stainless steel decreased from 32.737 nm to 13.917 nm. While the microbial adhesion tests showed the modified glass and stainless steel surface could reduce more than 90 % of the bacterial attachment rate.