| Summary: | 碩士 === 長庚大學 === 醫務管理學系 === 107 === Abstract
Objectives: The aim of the present study was to explore the association between sarcopenia and cognitive impairment among community dwelling older adults in Taiwan.
Methods: We analyzed cross-sectional data from a nationally representative sample of adults aged 65 years and older (n = 2904) participating in the 2009 National Health Interview Survey in Taiwan. In the present study, the Mini-Mental State Examination (MMSE) was used to assess cognitive function. The SARC-F (Slowness, Assistance walking, Rising from chair, Climbing stairs, and Falls) questionnaire was used as a rapid diagnostic test for sarcopenia. A total of 2710 participants who had complete data for demographic characteristics, chronic diseases, health behaviors, MMSE, and SARC-F were eligible for analysis. The Chi-Square test and multiple logistic regression models were used to evaluate the association between sarcopenia and cognitive impairment. To account for the complex sampling design, all analyses were carried out using SAS-callable SUDAAN.
Results: After adjustment for demographic characteristics, chronic diseases, and health behaviors, sarcopenia was associated with cognitive impairment (OR=2.44; 95% CI=1.43-4.14). After adjustment for demographic characteristics, chronic diseases, and health behaviors, compared to participants with no difficulty in assistance walking, participants who were with much difficulty or unable to had an OR for cognitive impairment of 3.40 (95% CI =1.00–11.56). After adjustment for demographic characteristics, chronic diseases, and health behaviors, compared to participants with no difficulty in rising from chair, participants who were with much difficulty or unable to had an OR for cognitive impairment of 5.23 (95% CI =1.09–25.23)
Conclusions: Our results show that the SARC-F scale can identify older adults who have higher odds of cognitive impairment. Further investigation is needed to explore the underlying causes of cognitive impairment in older adults with sarcopenia.
Keyword：sarcopenia and cognitive impairmen
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