| Summary: | 碩士 === 國立臺灣科技大學 === 應用科技研究所 === 106 === Wound dressings are an important part of wound care. The most prominent feature of
wound dressings is to keep the wounds moist, reduce the formation of scars, relieve the pain of the patients and avoid excessive fluid loss in the wounded. Hydrogel is currently a very common material for wound dressings, which are themselves very hygienic gels which, as a wound dressing, possess the above mentioned characteristics and, because of their inherently transparent nature, make it easier to observe wound healing Case. However, when the wound dressing is applied to the wound for a period of time, it may stick to the skin after absorbing the tissue fluid, which may cause secondary wound damage and discomfort to the patient while being removed. In this study, we attempted to study the reversible hydrogel as a wound dressing and use its reversible properties to remove the hydrogel from the wound. Pluronic F-127 is a thermoreversible hydrogel aterial whose principle of gelation is related to its concentration and temperature. As the temperature increases, it crosslinks to form a gel and returns to solution at low temperatures Alginate is also an ionic crosslinked hydrogel material that itself has a negative charge and therefore can coat positively charged materials such as small proteins. In this study, Pluronic F-127 blended with alginate are expected to be used as smart wound dressings, making it possible to use their properties to create thermal and ionic reversible wound dressings.
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