Targeting BRCAness Cancer Cells with DNA Alkylator and Its Derivatives
碩士 === 國立臺灣大學 === 生化科學研究所 === 106 === DNA interstrand cross-link (ICL) is one of the most cytotoxic lesions among many kinds of DNA damages. ICLs block essential cellular processes such as DNA replication and transcription, and thus generate DNA double-strand breaks (DSBs). It has been well document...
Main Authors: | Min-Yu Ko, 柯旻佑 |
---|---|
Other Authors: | Hung-Yuan Chi |
Format: | Others |
Language: | en_US |
Published: |
2018
|
Online Access: | http://ndltd.ncl.edu.tw/handle/brmt65 |
Similar Items
-
BRCAness in breast cancer
by: Irwin, Gareth William
Published: (2016) -
The ssDNA Theory of BRCAness and Genotoxic Agents
by: Panzarino, Nicholas J.
Published: (2021) -
BRCAness profile of sporadic ovarian cancer predicts disease recurrence.
by: Weiya Z Wysham, et al.
Published: (2012-01-01) -
DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma
by: Ameline, B., et al.
Published: (2021) -
BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy.
by: Hirokazu Tanino, et al.
Published: (2016-01-01)