Targeting BRCAness Cancer Cells with DNA Alkylator and Its Derivatives

碩士 === 國立臺灣大學 === 生化科學研究所 === 106 === DNA interstrand cross-link (ICL) is one of the most cytotoxic lesions among many kinds of DNA damages. ICLs block essential cellular processes such as DNA replication and transcription, and thus generate DNA double-strand breaks (DSBs). It has been well document...

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Bibliographic Details
Main Authors: Min-Yu Ko, 柯旻佑
Other Authors: Hung-Yuan Chi
Format: Others
Language:en_US
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/brmt65