| Summary: | 碩士 === 國立臺灣大學 === 化學研究所 === 106 === The spectral region in 1800~2500 cm-1 is well-known for the absence of interference signal from biomolecules such as proteins or carbohydrates. However, molecules with triple bond have signal in this region. So we choose molecules containing CC and CN triple bond that is, benzonitrile, 4-iodophthalonitrile, (triphenylsilyl)acetylene, 1,2-bis(triphenylsilyl)acetylene to test their signal intensity and position. Their signals on the gold chip upon serial dilution also behave like typical adsorption isotherm. Affinity on gold coated SERS substrate is also tested to evaluate the feasibility of using them as reporter molecules.
In addition to looking for appropriate molecules with signal in the 1800~2500 cm-1, SERS substrate with good sensitivity, reproducibility is also a desirable goal for sensing applications. We try to fabricate SERS substrate by a maskless reactive ion etching (RIE) process. Because SERS substrate is fabricated through the RIE procedure followed by e-beam evaporation of Au, it is crucial to adjust the RIE parameters (etching gas ratio, etching power) to get a nanostructure suitable for SERS signal generation, and the fabricated nanostructure could be identified through scanning electron microscopy images of fabricated substrates. Finally, SERS signals of the molecules on the in-house fabricated substrates demonstrate that we successfully fabricate a SERS substrate through a simple maskless process.
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