A Study on Dental Implant Design, Surface Modification and the Efficiency of Peri-implantitis Disinfection by Laser Treatment

• Main Authors: Kuo, Hsien-Nan, 郭獻南
• Other Authors: Chou, Jyh-Horng
• Format: Others
• Language: en_US
• Published: 2018
• Online Access: http://ndltd.ncl.edu.tw/handle/57qsvk

博士 === 國立高雄第一科技大學 === 工學院工程科技博士班 === 106 === With the prosperity of dental implantation, the development of dental implant in the future is not only the implantation to restore the chewing function of missing teeth, but also paying more attentionto the aesthetics after implantation and the long-term stability of the implants. Moreover, the infection of the implants can be treated without hurting the microstructure of the implants to avoid losing the implant and bone integration function. In this dissertation, the studies were conducted ranging from the structure of implant materials to surface modification treatment, and disinfection and sterilization of implant lesions. This paper first makes a comprehensive analysis of the market, technology and clinical aspects of artificial roots. The second part is to study the addition of titanium dioxide (TiO2) to zirconia (ZrO2) materials. The main reason is that TiO2 is a biocompatible material and a key component good for bone integration as well. It also has good mechanical properties even sintered at low temperature. The experimental results showed that when the microwave sintering is in the range of 1150℃~1300℃, the Vickers hardness could be in the range of 125-300Hv, and it increases with increasing TiO2 and temperature. The mechanical properties of this material are suitable for dental implants and their attachment such as crowns. The third part is the study of surface treatment of dental implant, the biocompatible silane and peptide is applied to the sandblasted/etched titanium plate. The experimental results showed the microstructure surface made of the materials has better hydrophilicity which can facilitate cell proliferation and mineralization, therefore accelerates the integration and stabilization of the bone.The fourth part is to evaluate the sterilization rate by using the Er:YAG laser to irradiate the peri-implantitis microbial E. coli, and combines CT and 3D printer to make a solid model as an experimental platform, and use real implants subjected to a sterilization experiment, the result of 98.9% sterilization rate was obtained which was in line with the clinical implementation requirements.