Computational Study of the Catalytic Mechanism of Ketol–Acid Reductoisomerase of Sso-ilvC2 Protein

碩士 === 國立中央大學 === 化學學系 === 106 === The ketol-acid reductoisomerase (KARI) is an enzyme necessary for the branched chain amino acids (BCAA) biosynthetic pathway. KARIs catalyze an alkyl-migration of substrate followed by a ketol-acid reduction in terms of NAD(P)H. However, the KARI reaction mechanism...

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Bibliographic Details
Main Authors: Sheng-Uei Weng, 翁聖崴
Other Authors: Hui-Hsu Tsai
Format: Others
Language:en_US
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/6cbsa7