| Summary: | 碩士 === 國立體育大學 === 運動科學研究所 === 106 === Purpose: This study is to evaluate whether the combination BEC of these two substances could ameliorate physical fatigue or increase exercise performance. Methods：A total of 40 male ICR mice were split into four groups (10 mice/group): (1 ) the control group without treatment (Vehicle), (2) 0.5-fold dosage of BEC (BEC-0.5X), (3) 1-fold of BEC (BEC-1X), and (4) 5-fold of BEC (BEC -5X). After 4 weeks, all mice were tested for exercise performance and anti-fatigue functions, including forelimb grip strength, endurance performance in a 5% body weight-loaded swimming test, and serum levels of lactate, ammonia, glucose, blood urea nitrogen, and creatine kinase after exercise challenge. Results：Showed that BEC-treated animals have a significant increase in endurance swimming performance, and both in a dose-depend manner. In addition, BEC-treated mice have a significant reduction of fatigue- or muscle injury-associated biomarkers in serum Lactate, ammonia, and glucose levels post an acute exercise challenge. In conclusion, our data confirmed that BEC supplementation has a great potential as an ergogenic aid. Conclusion：Our results suggest that continuous supplementation with BEC could increase exercise performance and reduce physical fatigue-associated serum levels of blood lactic acid and ammonia post exercise challenge.
Keywords：Chicken essence, swimming endurance, lactic acid, blood ammonia
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