The Comparison of Computed Tomographic images between nasal Transmissible Venereal Tumors (TVT) and non-TVT in dogs

• Main Authors: Po-Jiun Chen, 陳博駿
• Other Authors: 陳冠升
• Format: Others
• Language: en_US
• Published: 2018
• Online Access: http://ndltd.ncl.edu.tw/handle/32z824

碩士 === 國立中興大學 === 獸醫學系暨研究所 === 106 === Primary canine nasal and paranasal tumors comprise approximately 1%–2% of all canine neoplasia. Among the malignant nasal neoplasia, 60%–75% are carcinomas, and adenocarcinoma is over-represented. Because of the complexity of the canine nose structure and overlying bony structures, radiography does not always provide detailed information to determine the possible cause of nasal disease. Computed tomography (CT) is commonly used to recognize nasal neoplasia extension and tumor staging in dogs. The use of CT is essential for localization of tumors, involvement of lymph nodes, identification of adjacent affected tissues and distant metastasis. To the best of our knowledge, only one case report mentioned CT imaging of canine nasal transmissible venereal tumor (TVT). The purpose of this retrospective study is to describe CT features of confirmed nasal neoplasia in a group of dogs, and to determine whether there are specific findings to facilitate TVT diagnosis. We hypothesized that TVT may have different CT features from other nasal tumors. A total of 19 dogs were included: 6 with TVT, 9 with carcinoma, 1 with sarcoma, 2 with melanoma and 1 with mast cell tumor. We evaluated the quantitative and qualitative CT imaging features of TVT and other types of tumors. In the TVT group, mean Hounsfield Units (HU) was 49.56 HU (± 8.40) in the pre-contrast series and 89.89 HU (± 22.19) in the post-contrast series. In the non-TVT group, mean HU was 55.15 HU (± 15.12) in the pre-contrast series and 120.54 HU (± 22.46) in the post-contrast series. Statistically significance was found in mean post-contrast HU between TVT and carcinoma (p value = 0.014), but no significant relationship was found between the severity of bone invasion and tumor types (p value = 0.184). Stripe-enhancement pattern was noticed in the carcinoma, whereas TVT did not show this sign. In conclusion, the mean enhanced HU value in nasal TVT is lower than that in other types of tumors, and stripe-enhancement pattern may be a specific structure to distinguish carcinoma from TVT.