Development of Microfluidic Platform for Real-time Analysis to Detect the Quantity of Ephedrine in Different Formula

• Main Authors: LIN, JUNG-CHIH, 林榮志
• Other Authors: CHANG, HSING-CHENG
• Format: Others
• Language: zh-TW
• Published: 2018
• Online Access: http://ndltd.ncl.edu.tw/handle/x364dp

博士 === 逢甲大學 === 電機與通訊工程博士學位學程 === 106 === In this study, based on the centrifugal microfluidic detection technology, a real-time detection centrifugal microfluidic platform has been developed for detecting the content of traditional Chinese medicine compound ephedrine, which can be applied to the rapid detection and analysis of the quality components of traditional Chinese medicine. The ion-sensing film was fabricated by electrospinning on the micro-channel structure, and the ion detection electrode reaction was used to detect the index content of ephedrine in the traditional Chinese medicine preparation, and the correlation of the ephedrine content of different samples was investigated. The experimental results of the ephedrine-related reaction change the concentration accordingly. The concentration of ephedrine increases due to the increase of the sample dose, and the voltage response also mutates. The experimental ephedrine concentration ranges from 2.69 mg/g to 16.64 mg/g. The real-time ion detection technology of this system had been proved to provide quantigtative analysis for concentrated Chinese medicine preparations, which is beneficial to the rapid and accurate analysis and application of Chinese medicine ephedrine preparations and index components.