Design and Synthesis of Piperazine 10-Hydroxycamptothecin Glucuronide Prodrug

碩士 === 嘉南藥理大學 === 藥學系 === 106 === Camptothecin has good anti-cancer activity but have poor water solubility. For improving water solubility, our laboratory designed and synthesized two glucuronide prodrugs of Camptothecin (9-ACG and 10-HCG) which will mainly be activated at tumor site expressing lar...

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Bibliographic Details
Main Authors: CHEN, KUO-HUI, 陳國輝
Other Authors: LEU, YU-LIN
Format: Others
Language:zh-TW
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/38xur4