Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis
碩士 === 中國醫藥大學 === 牙醫學系碩士班 === 106 === Research background In recent years, with the popularization of 3D CT scanning and the development of 3D printing technology, it is increasingly popular for using titanium plates in the surgery for patients. Oral cancer ranks 5th in cause of cancer death, with a...
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碩士 === 中國醫藥大學 === 牙醫學系碩士班 === 106 === Research background
In recent years, with the popularization of 3D CT scanning and the development of 3D printing technology, it is increasingly popular for using titanium plates in the surgery for patients. Oral cancer ranks 5th in cause of cancer death, with a mortality rate of 12.48 per 100,000 people and ranks fourth in male cancer deaths. Face is important when people communicate face-to-face. However, after the surgery of mandibular excision for oral cancer, facial repair and restoration of chewing function are the goals of every clinician, therefore, how to repair the mandibular segmental defect is an important issue and is worth to be investigated.
Materials and methods
This study used an artificial mandible with anatomical shape and obtains its computed tomography (CT) image files. After importing those images into the medical imaging software, the specially designed 3D model of printed titanium prosthetic framework with mandibular anatomical shape were created. The analyzed parameters in the models of the 3D titanium mandibular prosthetic framework are as follows: 1. Two different surgical design, include: (1) the prosthesis retaining the residual mandibular bone (mild oral cancer patients) and (2) the prosthesis with complete mandibular resection (severe oral cancer patients); 2. Two different lengths of mandibular prosthesis: 20 mm and 25 mm; 3. Three different thickness of mandibular prosthesis: 0.8mm, 1mm and 1.5 mm. On the basis of the above three kinds of design parameters, a total of 12 groups of 3D model, were then put in to the finite element (FE) software for the simulation. A bite force of 100 newtons at a 45-degree angle from the lingual side to the buccal side was applied as loading condition, and the highest value and distribution of von-Mises stresses of the 3D model of printed scaffold and peripheral bone of the mandible were investigated.
Results
In the results of the two different surgical designs, whether the prosthesis retaining the residual bone or with complete mandibular resection, the high stresses of the prosthesis are concentrated at the two locations, one is on the junction of the lower edge of the dental-abutment column and another is on the left wing of the prosthesis. Compared with those two designs, the prosthesis retaining the residual mandibular bone has the highest stresses in the prosthesis and cortical bone. With the prosthesis model of thickness of 0.8 mm and length of 20 mm as an example, the peak stresses on the prosthesis and cortical bone in the design of the prosthesis with complete mandibular resection are 43.79 MPa and 10.51 MPa; however, the peak stresses in the design of the prosthesis retaining the residual mandibular bone are even higher, the stresses on the prosthesis and cortical bone are 46.83 MPa and 11.79 MPa. In the results of two lengths of prostheses, using prosthesis with the thickness of 0.8 mm as an example, the peak stress under lower edge of the dental-abutment column with the 25 mm of prosthesis length at is higher (compared with the 2.0mm of prosthesis length) (46.68 MPa vs. 38 MPa), but at the left wing of the prosthesis, the prosthesis stress with the length of 20 mm is higher (compared with the length of 25 mm) (46.83 MPa vs. 41.1 MPa). In the results of cortical bone stress, the model with 20 mm length of prosthesis bears more stress than that with 25 mm of length of prosthesis. Observing the models with 20 mm length of prosthesis retaining the residual mandibular bone as an example, the prosthesis stresses with thickness at 0.8 mm, 1 mm, 1.5 mm were 46.83 MPa, 42.47 MPa, 38.32 MPa, respectively, while the cortical bone stress were 11.79 MPa, 12.02 MPa, 13.37 MPa, correspondingly. Observing the
models of 20 mm length of prosthesis with complete mandibular resection as an example, the peak prosthesis stresses with thickness of 0.8mm, 1mm and 1.5mm were 43.79 MPa, 32.69 MPa and 31.35 MPa, respectively, but the peak cortical bone stresses were 10.51 MPa, 11.29 MPa and 12.16 MPa, individually.
Conclusion
In this study, it was found that under two different surgical designs, the stresses of prosthesis and cortical bone in the model of the prosthesis retaining the residual mandibular bone is higher as compared with the model of the prosthesis with complete mandibular resection. In the results related to prosthesis length, there is no fixed trend of prosthesis stress, but stress in the cortical bone is relatively high at the prosthesis length of 20 mm as compared with that of 25 mm. Both designs show that as the thickness of the prosthesis is decreasing, the stress in the prosthesis is decreasing also, but the stress in cortical bone is increasing. The results of in this study is still need to be confirmed in future clinical report.
Keywords: mandibular resection of oral cancer, mandibular segmental defect, 3D printed titanium mandibular prosthetic framework, the prosthesis retaining the residual mandibular bone, the prosthesis with complete mandibular resection, the prosthesis length, the prosthesis thickness, finite element analysis
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author2 |
Lih-Jyh Fuh |
author_facet |
Lih-Jyh Fuh Sheng-Ni Huang 黃聖霓 |
author |
Sheng-Ni Huang 黃聖霓 |
spellingShingle |
Sheng-Ni Huang 黃聖霓 Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
author_sort |
Sheng-Ni Huang |
title |
Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
title_short |
Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
title_full |
Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
title_fullStr |
Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
title_full_unstemmed |
Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis |
title_sort |
biomechanical evaluation of 3d printed titanium reconstruction/prosthetic framework for mandibular segmental osteotomy defect-finite element analysis |
publishDate |
2018 |
url |
http://ndltd.ncl.edu.tw/handle/3we227 |
work_keys_str_mv |
AT shengnihuang biomechanicalevaluationof3dprintedtitaniumreconstructionprostheticframeworkformandibularsegmentalosteotomydefectfiniteelementanalysis AT huángshèngní biomechanicalevaluationof3dprintedtitaniumreconstructionprostheticframeworkformandibularsegmentalosteotomydefectfiniteelementanalysis AT shengnihuang xiàègǔjiéduànxìngquēsǔnxiūfùzhī3dlièyìntàijīnshǔyànfùzhījiàdeshēngwùlìxuéfēnxīyǒuxiànyuánsùmónǐ AT huángshèngní xiàègǔjiéduànxìngquēsǔnxiūfùzhī3dlièyìntàijīnshǔyànfùzhījiàdeshēngwùlìxuéfēnxīyǒuxiànyuánsùmónǐ |
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spelling |
ndltd-TW-106CMCH50890012019-11-28T05:22:31Z http://ndltd.ncl.edu.tw/handle/3we227 Biomechanical Evaluation of 3D Printed Titanium Reconstruction/Prosthetic Framework for Mandibular Segmental Osteotomy Defect-Finite Element Analysis 下顎骨節段性缺損修復之3D列印鈦金屬贗復支架的生物力學分析-有限元素模擬 Sheng-Ni Huang 黃聖霓 碩士 中國醫藥大學 牙醫學系碩士班 106 Research background In recent years, with the popularization of 3D CT scanning and the development of 3D printing technology, it is increasingly popular for using titanium plates in the surgery for patients. Oral cancer ranks 5th in cause of cancer death, with a mortality rate of 12.48 per 100,000 people and ranks fourth in male cancer deaths. Face is important when people communicate face-to-face. However, after the surgery of mandibular excision for oral cancer, facial repair and restoration of chewing function are the goals of every clinician, therefore, how to repair the mandibular segmental defect is an important issue and is worth to be investigated. Materials and methods This study used an artificial mandible with anatomical shape and obtains its computed tomography (CT) image files. After importing those images into the medical imaging software, the specially designed 3D model of printed titanium prosthetic framework with mandibular anatomical shape were created. The analyzed parameters in the models of the 3D titanium mandibular prosthetic framework are as follows: 1. Two different surgical design, include: (1) the prosthesis retaining the residual mandibular bone (mild oral cancer patients) and (2) the prosthesis with complete mandibular resection (severe oral cancer patients); 2. Two different lengths of mandibular prosthesis: 20 mm and 25 mm; 3. Three different thickness of mandibular prosthesis: 0.8mm, 1mm and 1.5 mm. On the basis of the above three kinds of design parameters, a total of 12 groups of 3D model, were then put in to the finite element (FE) software for the simulation. A bite force of 100 newtons at a 45-degree angle from the lingual side to the buccal side was applied as loading condition, and the highest value and distribution of von-Mises stresses of the 3D model of printed scaffold and peripheral bone of the mandible were investigated. Results In the results of the two different surgical designs, whether the prosthesis retaining the residual bone or with complete mandibular resection, the high stresses of the prosthesis are concentrated at the two locations, one is on the junction of the lower edge of the dental-abutment column and another is on the left wing of the prosthesis. Compared with those two designs, the prosthesis retaining the residual mandibular bone has the highest stresses in the prosthesis and cortical bone. With the prosthesis model of thickness of 0.8 mm and length of 20 mm as an example, the peak stresses on the prosthesis and cortical bone in the design of the prosthesis with complete mandibular resection are 43.79 MPa and 10.51 MPa; however, the peak stresses in the design of the prosthesis retaining the residual mandibular bone are even higher, the stresses on the prosthesis and cortical bone are 46.83 MPa and 11.79 MPa. In the results of two lengths of prostheses, using prosthesis with the thickness of 0.8 mm as an example, the peak stress under lower edge of the dental-abutment column with the 25 mm of prosthesis length at is higher (compared with the 2.0mm of prosthesis length) (46.68 MPa vs. 38 MPa), but at the left wing of the prosthesis, the prosthesis stress with the length of 20 mm is higher (compared with the length of 25 mm) (46.83 MPa vs. 41.1 MPa). In the results of cortical bone stress, the model with 20 mm length of prosthesis bears more stress than that with 25 mm of length of prosthesis. Observing the models with 20 mm length of prosthesis retaining the residual mandibular bone as an example, the prosthesis stresses with thickness at 0.8 mm, 1 mm, 1.5 mm were 46.83 MPa, 42.47 MPa, 38.32 MPa, respectively, while the cortical bone stress were 11.79 MPa, 12.02 MPa, 13.37 MPa, correspondingly. Observing the models of 20 mm length of prosthesis with complete mandibular resection as an example, the peak prosthesis stresses with thickness of 0.8mm, 1mm and 1.5mm were 43.79 MPa, 32.69 MPa and 31.35 MPa, respectively, but the peak cortical bone stresses were 10.51 MPa, 11.29 MPa and 12.16 MPa, individually. Conclusion In this study, it was found that under two different surgical designs, the stresses of prosthesis and cortical bone in the model of the prosthesis retaining the residual mandibular bone is higher as compared with the model of the prosthesis with complete mandibular resection. In the results related to prosthesis length, there is no fixed trend of prosthesis stress, but stress in the cortical bone is relatively high at the prosthesis length of 20 mm as compared with that of 25 mm. Both designs show that as the thickness of the prosthesis is decreasing, the stress in the prosthesis is decreasing also, but the stress in cortical bone is increasing. The results of in this study is still need to be confirmed in future clinical report. Keywords: mandibular resection of oral cancer, mandibular segmental defect, 3D printed titanium mandibular prosthetic framework, the prosthesis retaining the residual mandibular bone, the prosthesis with complete mandibular resection, the prosthesis length, the prosthesis thickness, finite element analysis Lih-Jyh Fuh 傅立志 2018 學位論文 ; thesis 81 zh-TW |