Effect of whole body vibration in individuals with Parkinson's disease A systematic review and meta-analysis

• Main Authors: Ming Fong Lee, 李明峯
• Other Authors: K. Y. Lee
• Format: Others
• Language: zh-TW
• Published: 2018
• Online Access: http://ndltd.ncl.edu.tw/handle/nw2m8k

碩士 === 長庚大學 === 職能治療學系 === 106 === Background Parkinson disease is a neuro-generative disease, which leads to sensory, motor and cognitive symptoms. The application of whole body vibration on individuals with Parkinson disease dates back to the 19th century by a neurophysiologist, Jean Marie Charcot. His patients reported that their symptoms were ameliorated during traveling by trains. Although whole body vibration was widely applied on various population, the mechanism and treatment effect still remains unclear. The purpose of this research is to systematically summarize the effect of whole body vibration in individuals with Parkinson disease by using systematic review and meta-analysis. Methods We followed the PRISMA guideline to conduct this study. We searched several database including google scholar, Medline, CINHAL and Cochrane with seven keywords. Each literature was carefully reviewed based on the selection criteria and evaluated by The PEDro Scale. Comprehensive Meta Analysis Version 3 was used to generate the meta-analysis results. Result Ten articles were included in the systematic review and seven of them were selected for the meta-analysis. The findings suggested that the effect of whole body vibration was hard to be compared and inconsistent because of unstandardized treatment protocols, various outcome measures, different characteristics of participants in these studies. The meta-analysis results indicated contradicted findings. In the domain of static balance, the results favored the experiment group with the low to moderate effect size (0.360, P=0.009). For the motor function, the results also favored the experiment group with the medium effect size (-0.437, P<0.001). Unified Parkinson Disease Rating Scale total score favored the experiment group, the effect size was 0.596 (P<0.001). Discussion Few studies (N = 10) were included to examine the effect of whole body vibration in individuals with Parkinson disease, and the heterogeneous methodology among these studies may lead to inconclusive findings. Furthermore research with rigorous study design was required to draw the conclusion.