Pathogenic Investigation of Leber’s Hereditary Optic Neuropathy: Using Patient-Specific iPSCs-derived Retinal Ganglion Cells as a Diseased Platform
碩士 === 國立陽明大學 === 藥理學研究所 === 105 === Leber’s hereditary optic neuropathy (LHON) is a maternally inherited mitochondrial disease caused by homoplasmic point mutations in Complex I subunit genes of mitochondrial DNA. LHON is characterized by incomplete penetrance, as only part of Complex I mutation ca...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2017
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| Online Access: | http://ndltd.ncl.edu.tw/handle/8z523p |