Investigating the Dependence of T Cell Receptor Triggering on CD45 Segregation
博士 === 國立陽明大學 === 分子醫學博士學位學程 === 105 === Current understanding of T cell receptor (TCR) triggering is based on the segregation of membrane tyrosine phosphatases having large ectodomains upon engagement between T cells and antigen presenting cells, thereby creating a kinases/phosphatases imbalance to...
Main Authors: | Mohammad Ameen Al-Aghbar, 歐默漢 |
---|---|
Other Authors: | Steve R Roffler |
Format: | Others |
Language: | en_US |
Published: |
2017
|
Online Access: | http://ndltd.ncl.edu.tw/handle/34992363163963417313 |
Similar Items
-
High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation
by: Mohammad Ameen Al-Aghbar, et al.
Published: (2018-04-01) -
The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering
by: Bing-Mae Chen, et al.
Published: (2017-07-01) -
Nanoscale kinetic segregation of TCR and CD45 in engaged microvilli facilitates early T cell activation
by: Yair Razvag, et al.
Published: (2018-02-01) -
T-cell antigen receptor signal transduction in CD45-null thymocytes
by: Stone, John David
Published: (1997) -
CD45RB Status of CD8+ T Cell Memory Defines T Cell Receptor Affinity and Persistence
by: Scott M. Krummey, et al.
Published: (2020-02-01)