Development of multiplexed localized surface plasmon resonance (LSPR) biosensors and sensitivity enhancement techniques based on enzymatic reaction
碩士 === 國立陽明大學 === 生醫光電研究所 === 105 === In recent year, localize surface plasma resonance (LSPR) biosensor develops rapidly. In our experiment, using disposable gold nanostructures chips and enzymatic reaction for Matrix metallopeptidase 9 (MMP-9) detection. It is detected by simple optic setup. Dispo...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2017
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| Online Access: | http://ndltd.ncl.edu.tw/handle/66261863511160227779 |
| Summary: | 碩士 === 國立陽明大學 === 生醫光電研究所 === 105 === In recent year, localize surface plasma resonance (LSPR) biosensor develops rapidly. In our experiment, using disposable gold nanostructures chips and enzymatic reaction for Matrix metallopeptidase 9 (MMP-9) detection. It is detected by simple optic setup. Disposable LSPR chips can cut costs, mass manufacture and low consume. And then using enzymatic reaction to produce precipitation for the change of surface refractive index. The change signal is positive correlation to MMP-9 concentration. In our experiment, it can be detect 1 femtomolar.
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