| Summary: | 碩士 === 慈濟大學 === 公共衛生學系碩士班 === 105 === Background: Developmental Origins of Health and Disease (DOHaD) theory demonstrated that disease may originate from the maternal malnutrition during pregnancy. Low birth weight is often used as an indicator of the nutritional status of the uterus. Previous studies found that low birth weight infants had the worse development of cognitive function, neurodevelopment, and motor function. However, several studies did not found differences among children with later age.We aimed to examine the association between low birth weight and child development among preschool age children. Methods: This study was a retrospective study, and a total of 982 children were eligible. Based on the norm of birth weight and gestational age, we separated children into SGA (small for gestational age, n=116)group and non-SGA group (n=866). Multiple regression analysis was used to explore the relationship between SGA and preschool child development. Results: Except gestational age and birthweight, all other child-related and parental factors were similar among the two groups. Univariate analysis results indicated that SGA group had lower developmental scores in Fine motor, Conceptual comprehension, and Self help compared to the non-SGA group. When adjusting for other potential confounding factors, there were marginal significant differences in the situation comprehension and personal-social development among the two groups. The same finding was found in children under 3 years of age. For children above 3 years of age, only a marginal significancs in personal-social was found, that is the mean score in SGA group was lower than non-SGA group.Conclusions: Our results indicated that SGA children had similar developmental score compared to non-SGA children.
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