Integration of nanofluidic preconcentrator and particle separation for a particle controllable device

碩士 === 國立臺灣大學 === 應用力學研究所 === 105 === In this thesis, we have successfully integrated preconcentration mechanism and electrophersis separation. Fabricate a detection chip by coupling microchannels which including two channels: concentration channel and buffer channel, and Nafion as ion selection mem...

Full description

Bibliographic Details
Main Authors: Syu-Sheng Siao, 蕭旭昇
Other Authors: Horn-Jiunn Sheen
Format: Others
Language:zh-TW
Published: 2017
Online Access:http://ndltd.ncl.edu.tw/handle/xmh5vp
Description
Summary:碩士 === 國立臺灣大學 === 應用力學研究所 === 105 === In this thesis, we have successfully integrated preconcentration mechanism and electrophersis separation. Fabricate a detection chip by coupling microchannels which including two channels: concentration channel and buffer channel, and Nafion as ion selection membrane which crossing two channels. Preconcentration mechanism is applying a voltage drop in Nafion ends at first, can produce ion concentration polarization (ICP) which refers to one of the end becomes ion enrichment and the other becomes ion depletion. Then we apply a bias voltage to generate electroosmosis of the second kind to aggregate the preconcentration plug near the ion depletion region on the high voltage side. The separation system is applying electrophoresis technique to make particles which have different net charge moving in different velocity. The particle velocity in flow field and electric field is affected by sudden contraction flow channel. Different size particles have different net charge. We can make different size particle separated in different velocity.