| Summary: | 碩士 === 國立東華大學 === 化學系 === 105 === Heparan sulfate is a widely recognized carbohydrate with a variety of physiological activities that recognizes a wide variety of related proteins and intervenes in its protein-protein interactions, including chemokines and growth factors, etc. Hepatoma-derived growth factor is considered to be an important protein for the development of hepatocellular carcinoma. It has the function of promoting cell proliferation, which can bind to the DNA in the nucleus and act as a chemotactic growth factor and cell membrane , Therefore, we use nuclear magnetic resonance instruments to explore the role of hepatoma-derived growth factor and heparan sulfate analogue (8 mer) in the structure of proteins and sugars, as well as their respective structural changes, whereby the proposed structural model demonstrates .
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