n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryprophan 2,3 dioxygenase in spinocerebellar ataxia type 3
博士 === 國立東華大學 === 生命科學系 === 105 === Spinocerebellar ataxia type 3 or Machado-Joseph disease (SCA3/MJD) is characterized by the repetition of a CAG codon in the ataxin-3 gene (ATXN3), which leads to the formation of an elongated mutant ATXN3 protein that can neither be denatured nor undergo proteolys...
Main Author: | Karthyayani Rajamani |
---|---|
Other Authors: | Tzyy-Wen Chiou |
Format: | Others |
Published: |
2016
|
Online Access: | http://ndltd.ncl.edu.tw/handle/tfda5y |
Similar Items
-
Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia
by: Jeanne Hsieh, et al.
Published: (2017-10-01) -
<i>n</i>-Butylidenephthalide Modulates Autophagy to Ameliorate Neuropathological Progress of Spinocerebellar Ataxia Type 3 through mTOR Pathway
by: Jui-Hao Lee, et al.
Published: (2021-06-01) -
Molecular diagnosis of spinocerebellar ataxias and studies of pathogenesis of spinocerebellar ataxia type 3 and type 7
by: Hui-Fang Tsai, et al.
Published: (2005) -
Intrafamilial phenotypic variation in spinocerebellar ataxia type 23
by: Shunichi Satoh, et al.
Published: (2020-06-01) -
Spinocerebellar Ataxia
by: J Gordon Millichap
Published: (1988-07-01)