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• Main Authors: Yi-Jun Chen, 陳怡君
• Other Authors: Chin-Hang Shu
• Format: Others
• Language: zh-TW
• Published: 2017
• Online Access: http://ndltd.ncl.edu.tw/handle/09058192105528075667

碩士 === 國立中央大學 === 化學工程與材料工程學系 === 105 === 2-phenylethanol is widely used in the cosmetics and perfumery for fragrance modification with rose-like fragrance. Every year about 10000 tons of 2-phenylethanol are produced worldwide, the most of which through chemical synthesis. The chemical synthesis of 2-phenylethanol can be done by Friedel-Craft reaction. Though inexpensive, these processes are disadvantaged by low selectivity for the desired product and accompanied by the formation of toxic by-products. This makes the chemical production of 2-phenylethanol detrimental to the environment and health. Therefore, legislations of the US and EU have restricted the use of chemical 2-phenylethanol in cosmetics and food products. Therefore, how to replace the 2-phenylethanol by the chemical synthesized has become the trend of industrial development through the lower cost and the principle of protecting the environment, such as the use of microbial fermentation is becoming an alternative platform. Yeast fermentation has become the focal point of research effort utilizing the Ehrlich pathway wherein the L-phenylalanine is converted to 2-phenylethanol. However, 2-phenylethanol and ethanol have common inhibitory effect for yeast fermentation. Many studies had proved that product can be removed through in situ product removal techniques and the yield of product will increase. In this study, owing to the sponges have the hydrophobic property, it can adsorb 2-phenylethanol. So, we use the PDMS sponges to remove 2-phenylethanol, in order to reduce the inhibitory effect. By using the PDMS sponges, the yield of product can be increased and the extracted energy cost can be reduced.