Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons

碩士 === 中原大學 === 化學研究所 === 105 === The use of D-xylose as a starting material, the use of asymmetric synthesis of palm pond method, the rapid establishment of the required three-dimensional position of the main structure of the compound, and then use Wittig reagent to establish terminal double bond,...

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Main Authors: Yu-Lin Ho, 賀有鄰
Other Authors: Yow-Fu Tsai
Format: Others
Language:zh-TW
Published: 2017
Online Access:http://ndltd.ncl.edu.tw/handle/8nah24
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spelling ndltd-TW-105CYCU50650462019-05-15T23:39:16Z http://ndltd.ncl.edu.tw/handle/8nah24 Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons 具多樣性神經鞘氨醇之不對稱合成的開發研究:具十八個碳之神經鞘胺醇的合成 Yu-Lin Ho 賀有鄰 碩士 中原大學 化學研究所 105 The use of D-xylose as a starting material, the use of asymmetric synthesis of palm pond method, the rapid establishment of the required three-dimensional position of the main structure of the compound, and then use Wittig reagent to establish terminal double bond, and the introduction of Grubbs II reagent The desired long carbon chain, and finally the SN2 reaction to establish the backward position of the amine, and then hydrogenation to remove all the protective groups, through 15 steps to get the target product of sphingosine alcohol. Yow-Fu Tsai 蔡祐輔 2017 學位論文 ; thesis 45 zh-TW
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language zh-TW
format Others
sources NDLTD
description 碩士 === 中原大學 === 化學研究所 === 105 === The use of D-xylose as a starting material, the use of asymmetric synthesis of palm pond method, the rapid establishment of the required three-dimensional position of the main structure of the compound, and then use Wittig reagent to establish terminal double bond, and the introduction of Grubbs II reagent The desired long carbon chain, and finally the SN2 reaction to establish the backward position of the amine, and then hydrogenation to remove all the protective groups, through 15 steps to get the target product of sphingosine alcohol.
author2 Yow-Fu Tsai
author_facet Yow-Fu Tsai
Yu-Lin Ho
賀有鄰
author Yu-Lin Ho
賀有鄰
spellingShingle Yu-Lin Ho
賀有鄰
Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
author_sort Yu-Lin Ho
title Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
title_short Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
title_full Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
title_fullStr Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
title_full_unstemmed Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
title_sort studies on the development of the asymmetric synthesis of various sphinganines:synthesis of sphinganine with eighteen carbons
publishDate 2017
url http://ndltd.ncl.edu.tw/handle/8nah24
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