Porous carbon derived from metal-organic gels embedded polymer monolithic column for solid-phase microextraction of catecholamines

• Main Authors: Meng-Ju Hsu, 徐夢孺
• Other Authors: Hsi-Ya Huang
• Format: Others
• Language: zh-TW
• Published: 2017
• Online Access: http://ndltd.ncl.edu.tw/handle/76166867231478340565

碩士 === 中原大學 === 化學研究所 === 105 === In the present study, the porous carbon material derived from metal-organic gels (cMOGs) was defined as cAl-BDC-NH2, which embedded with polymer monolithic column for solid-phase microextraction (SPME) of catecholamine. In this experiment, cAl-BDC-NH2-poly(butyl methacrylate-ethylene dimethacrylate) (cAl-BDC-NH2-poly(BMA-EDMA)) was used to optimize the extraction parameters, and the results of the extraction steps were detected by micellar electrokinetic capillary chromatography (MEKC). Finally, the compare of the catecholamine extraction effect with metal-organic gels (Al-BDC-NH2-poly(BMA-EDMA)), different metal centers (cCr-BDC-NH2-poly(BMA-EDMA)) and embedded with different integrally formed polymers (cAl-BDC-NH2-poly(Sty-DVB)). The results showed that the optimum conditions were 36% cAl-BDC-NH2-poly(BMA-EDMA), 5 cm column length, 5 mM phosphate sample matrix at pH 7, ACN as washing solvent and 40 mM phosphate buffer in 30% methanol at pH 2 as the desorption solvent, the recovery was 50.3% to 97.2%. In this study, cMOGs-polymer extraction column were successfully prepared and applied to SPME of catecholamines compounds, which were highly polar biological analytes.