Impact of Antimicrobial Stewardship Program Interventions on the distribution of drug-resistant bacteria in a Hospital in Southern Taiwan

• Main Authors: WU,YA-FENG, 吳雅鳳
• Other Authors: LU,HAI-LIN
• Format: Others
• Language: zh-TW
• Published: 2017
• Online Access: http://ndltd.ncl.edu.tw/handle/w7zgqt

碩士 === 嘉南藥理大學 === 醫務管理系 === 105 === Since the discovery of penicillin in 1928, the era of antibiotic therapy has been opened. As the antibiotics are widely used, humans face a new crisis - the multidrug-resistant organisms (MDROs) appear to threaten the human health, the problems of drug resistance have caused human health shocks. According to the National Health Research Institutes "Taiwan Surveillance of Antimicrobial Resistance (TSAR)" I-VII (1998 ~ 2010) survey, the domestic multi-drug resistant organisms (MDROs ) Has risen gradually and is one of the most serious in the world. U.S. Food and Drug Administration(FDA) approved the listing of antibiotics from 1983 to 2011 the number of declining , the past 20 years has not introduced a new class of antibiotics, according to statistics estimated that 5 to 10 years will not have a new role in the machine Antibiotics can be used clinically .The Ministry of Health and Welfare has implemented an National Action Plan. Antimicrobial Stewardship Program since 2013. It is hoped that through the implementation of the program, we will allow you to face up to the problem of drug resistance and promote the rational use of antibiotics. Because the participation in antibiotic management program, to understand the abuse of antibiotics caused serious problems, would like to collect the hospital nearly six years of drug-resistant strains of bacteria, to understand our hospital strains of drug resistance trends and plans before and after the implementation of multiple anti- Whether there is improvement in the production of the situation, and further explore the patient population which patients are more likely to cause antibiotic abuse caused by multiple drug-resistant strains of infection, and increase the cost of medical expenses, but also the need for prudent use of antibiotics . According to the data collected, the common pathogenic bacteria in our hospital are: Escherichia coli、Klebsiella pneumoniae 、Pseudomonas aeruginosa、Acinetobacter baumannii、 Staphylococcus aureus and Enterococcus spp. We monitor the proportion of these strains is also increasing the trend of rising year by year, and in the patient population is the intensive care unit and blood cancer patients and elderly .A higher proportion of drug-resistant bacteria