Full-field optical coherence tomography for three-dimensional dermal tissue imaging

• Main Authors: Yu-Yen Wang, 王友延
• Other Authors: Yu-Shan Juan
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/g952pb

碩士 === 元智大學 === 光電工程學系 === 104 === Conventional handheld skin cameras are suitable for two-dimensional (2D) inspection of shallow skin. With noninvasiveness and high resolution, optical coherence tomography (OCT) has become a popular medical imaging technology. Among OCT schemes, full-field optical coherence tomography (FF-OCT) is suitable for rapid three-dimensional (3D) imaging, as it uses a 2D imaging device for pixel processing of a sample plane. Conventionally, the use of low-coherent infrared light sources in OCT resulted in monochromatic images. As light emitting diode (LED) has advantages of wide bandwidth and long lifetime, RGB LEDs were applied in an FF-OCT system in this study to establish full-color skin imaging system by overlapping the respective red (R), green (G) and blue (B) tissue images. In this thesis, the experiment results such as full-color melanin images of a guppy, 3D skin images of a hog, and 3D skin images of human face show the potential of RGB LED sources in FF-OCT applications for dermal tissue imaging. The skin imaging system shown in the study could be miniaturized to a handheld model. Due to its non-invasiveness, high spatial resolution and the potential for full-color or 3D imaging, this imaging system can further be applied in the fields of skin science, dermatology and cosmetology.