| Summary: | 碩士 === 淡江大學 === 機械與機電工程學系碩士班 === 104 === This study explores open-angle glaucoma and its Pathogenesis to create the whole Numerical model and Mechanical analysis. Open-angle glaucoma is caused by pathological changes of trabecular meshwork. Intraocular aqueous fluid will be stuck and intraocular pressure will increase in both anterior and posterior chamber. Then, intraocular pressure of posterior chamber diffuses and oppress optic disc, causes the blurring and disability of sight.
This study apply two software, 3D Design software PROE and Finite element method simulation software ANSYS, to create mode and related simulation of open-angle glaucoma. This simulation analysis helps us to understand pressure distribution of glaucoma and where the stress gathers in different Cup-disc ratio.
This study analyzes stress distribution in different Cup-disc ratio of open-angle glaucoma. I do different researches based on Cup-disc ratio degree from 0.3 to 0.7. Under the same condition, I find from degree 0.3 to 0.7, surface depression shows that stress tends to get close to optic disc. Besides, where the stress gathers differs in different surface depression, so I also conduct numerical analysis based on different stress-gathering section.
The result of analyzing open-angle glaucoma can help the patient understand more about the cause of open-angle glaucoma. In addition, because Cup-disc ratio degree is the main cause of open-angle glaucoma, this study can also offer simulated data of reference value in medical use in the future.
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