| Summary: | 碩士 === 南臺科技大學 === 生物科技系 === 104 === Introduction
Cancer has been the first in ten deaths in Taiwan, liver cancer is the top two causes of death among all cancers, each year about more than one million new patients, causing more than 7,000 deaths. Most liver cancer patients with B, C liver virus infection. Liver cancer therapy include: transcatheter arterial embolization, alcohol injection, radiofrequency ablation, traditional liver resection, liver transplantation, chemical or target drug therapy and so on.
Aim of study
This study was aimed to explore the south a medical center, collecting 500 liver cancer patients, tracking since January 1, 2009 to the end of January 2014, through a liver transplant, the traditional liver resection, radiofrequency tumor ablation, arterial perfusion chemical embolization, these four treatment recurrence rate and survival, do discussions and analysis in accordance with the treatment results, give patients more desirable quality of life and the future more ideal treatment approach.
Materials and methods
In this study, assessment of survival and recurrence rate of assessment project: HCC tumor staging, Seventh Edition (AJCC), Barcelona clinical liver cancer staging (BCLC), and predict the prognosis of HCC assessment project is Cancer of Italian Program (CLIP).Discussion relapse factors which have Bil-T, AFP, GOT and GPT, Albumin, PT INR, Platelet, by the above data to explore factors relapse after treatment, the tumor may recur circumstances do judgment.
Results
Discussion tumor stage (AJCC and BCLC) staging presented sooner the better cure its efficacy, and to find medical treatment, radiofrequency ablation prognosis better prognosis than TACE; to render surgical treatment, liver transplantation prognosis than conventional liver tumor resection good，liver cancer recurrence after treatment on the check value analysis and testing, which received local treatment after relapse, it Bil-T average more than 1.5mg / dl or more, confirming the localized treatment effect really bad, there may be a tumor has not been cut off, once relapse, thus increasing the bilirubin; while AFP is the most meaningful indicator of liver cancer, especially when the hepatic artery perfusion technique relapse compared chemoembolization and liver transplant, this the most representative of recurrence; in analyzing common GOT and GPT index, relapse after treatment is still in its localized 200IU / L or more; albumin represents the degree of inflammation nutritional status and disease, in order to influence long-term One of the most important factor in survival, recurrence and no recurrence of four treatment compared to the results of small difference; after PT INR if extended, on behalf of patients with liver cancer, the more the degree of liver damage, receiving partial treatment of relapse there are obvious coagulopathy; Finally platelets , because the causes of liver cancer caused by low platelet splenomegaly, and hepatic artery chemoembolization perfused platelets recurrence an average of only 100,000, compared with surgery, cancer The presence also makes clotting function deteriorated.
Conclusion
According to our southern liver cancer patients with surgery, the liver transplantation will have a higher survival rate and lower recurrence rates than conventional liver tumor surgery; in terms of medical treatment, radiofrequency ablation of hepatic tumor than chemoembolization have a higher survival rate and lower recurrence rate, on the whole, liver transplantation has been shown to be an effective method of treatment.
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