High Sensitivity IGZO-TFT Biosensors for EBV Protein Detection

• Main Authors: Tsung-Han Yang, 楊宗翰
• Other Authors: Jian-Jang Huang
• Format: Others
• Language: en_US
• Published: 2016
• Online Access: http://ndltd.ncl.edu.tw/handle/83948124199095843875

碩士 === 國立臺灣大學 === 光電工程學研究所 === 104 === In this thesis, a biosensor consists of an Indium-Gallium-Zinc-Oxide (IGZO) thin film transistor (TFT) biosensor and a gold sensing pad is demonstrated. There are two parts in this thesis. In the first part, a TFT biosensor with an extended gold sensing pad is demonstrated. EBV antibodies are measured and the results are compared with three conventional biological detection methods to ensure the reliability of the TFT biosensor. Time-saving and high sensitivity are the significant advantages. The TFT biosensor is able to selectively detect 10-5µg/ml EBV antibodies in the PBS buffer solution. In the second part, a modified reusable TFT biosensor is demonstrated. The TFT section and the sensing pad section of the biosensors are separated and then combined by wire bonding. The main advantage is that TFT transistors can be reused after each measurement by substituting the external gold sensing pads. A Cross-matching comparison of ELISA approach and TFT biosensor is discussed in order to verify reliability and credibly of the TFT biosensor.