| Summary: | 碩士 === 國立清華大學 === 工程與系統科學系 === 104 === Human exhaled breath measurement is one of important non-invasive health monitoring methods. The symptoms of bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD) are similar, but different treatments for these two diseases. In this research, thermal desorption (TD) tendon with gas chromatography–mass spectrometry (GC-MS) system has been used to develop a screen method for the COPD patients, BA patients, and normal people.
In this research, “Cyclotrisiloxane, hexamethyl-“has been used as an internal standard for the evaluation of the relative concentration for all the detected volatile organic compounds (VOCs). First, we compare the relative concentration of VOCs from empty airbags and from the samples that were exhaled from COPD, BA patients, and normal people. Then, decision tree with deliberately ordered VOCs is used to identify the situation of every object. Cross validation is used to verify the data between the certain groups of samples. The breath from these three kinds of people could be simply distinguished and the average classification accuracy of normal people, COPD patients and BA patients are 100%, 94% and 70% respectively.
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