| Summary: | 碩士 === 國立臺中教育大學 === 體育學系碩士班 === 104 === Ginseng is one of popular herbs around the world. The saponin extracts from ginseng mainly composed of Rg1 and Rb1. The previous human studies suggested that ginseng supplements could improve physiological capacities including environment adapting, anti-fatigue and anti-inflammation. The purpose of the study was to investigate the ergogenic properties of ginsenoside Rg1 on glycogen re-synthesis in exercised human skeletal muscle. Methods: In a randomized double blind study, twelve healthy male subjects were supplemented Rg1 (5 mg) or placebo 60 minutes prior to a 60-min cycling exercise with 70% VO2max. All subjects ingested a high carbohydrate meal (2 g carbohydrate/kg body weight, 80% carbohydrate, 8% fat, 12% protein) immediately after exercise. Muscle biopsy samples were obtained from vastus lateralis immediately and 3 h after exercise. Simultaneously, blood and gas samples were collected before exercise and during 3-h recovery period. Results: We found that acute oral Rg1 supplementation significantly enhanced muscle glycogen re-synthesis compared to placebo supplementation(P<.05), However, no significant differences in glucose levels, insulin levels, non-estesterified fatty acid levels and respiratory exchange ratio between Rg1 and placebo trials. Therefore, the present study demonstrated that acute oral Rg1 supplementation could enhance glycogen re-synthesis in exercised human skeletal muscle.
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