| Summary: | 碩士 === 國防醫學院 === 護理研究所 === 104 === Background: Migraine is a common health problem. More than 14.2% of adults over 18 years old have terrible experience with migraine or severe headache. The most common causes of migraine disability were characteristics of pain including pain intensity, duration, and frequency. Also, migraine disability may be affected by time. The purpose of this study is to assess the relationship of migraine disability and characteristics of pain , examine developmental trajectory patterns of migraine disability among migraineurs and determine the relative risks in explaining the trajectories patterns of migraine disability.
Methods: The study was an observational longitudinal study with a 3-month and 6-month follow-up. One hundred and twenty-seven migraineurs (78.7% in women and 21.3% in men) were recruited in this study. Data was obtained from a neurology clinic of hospital center in northern Taiwan. Participants diagnosed migraine with/without aura were asked to complete the questionnaires including demographic features, Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index (PSQI), and Migraine Disability Assessment (MIDAS). SPSS 20.0 software package for descriptive statistical analysis and generalized estimating equation, latent class growth model, and multiple logistic regression analysis for inferential statistical analysis were used. P value <0.05 was considered statistically significant.
Results: Migraine disability were associated with gender, pain intensity, duration, frequency and using prevent agents; suzin could significantly reduce migraine disability than other preventive agents; the migraine disability can be divided into three trajectory patterns, flat decrease without disability group (47.9%), moderate decrease with mild disability group (45.8%), and sharp decrease with severe disability group (6.3%); In comparison with the “flat decrease without disability group”, “moderate decrease with mild disability group” was related to family history of migraine, menstruation, pain intensity, duration, frequency, taking painkillers days, and using prevent agents; In comparison with the “flat decrease without disability group”, “sharp decrease with severe disability group” was related to the total number of comorbidities, duration, taking painkillers days, anxiety, depression, and sleep quality.
Conclusions: These findings can be used as reference for help health care workers to identify high-risk group of migraine disability trajectory, and be able to provide appropriate medical care and treatments.
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