Real-time sensing tip for aqueous NO with optical fibers embedded in active hydrogel waveguide

• Main Authors: Chung, Chieh-Wen, 鍾絜雯
• Other Authors: Zan, Hsiao-Wen
• Format: Others
• Language: en_US
• Published: 2016
• Online Access: http://ndltd.ncl.edu.tw/handle/7sh6j4

碩士 === 國立交通大學 === 光電工程研究所 === 104 === In this thesis, we present a highly sensitive and sharp Nitric oxide (NO) sensing tip based on a homogeneously active optical waveguide made of the hydrogel Poly 2-hydroxyethyl methacrylate (PolyHEMA) which mixed with 1, 2-Diaminoanthraquinone (DAQ) as the probe molecule. This real-time solid-state hydrogel sensing tip is made by inserting two parallel optical fibers inside a PolyHEMA hydrogel waveguide. With controlling the distance between the two fibers, we create a switch-like sensor which the light in fibers has to propagate through the 1mm distance from the in-coming fiber to the out-coming fiber. The light intensity collected by the out-coming fiber therefore depends sensitively on the absorption coefficient changed by the NO concentration. The overall diameter of the sensing tip is only 1.2 mm and housed in a needle whose diameter is about 1.6 mm to avoid possible mechanical stress and distortion in practices. Such diameter is sharp enough for skin or organ penetration in medical applications above.