| Summary: | 碩士 === 國立成功大學 === 物理治療學系 === 104 === Background and Purpose: Genioglossus muscle and inspiratory muscle have been showed contributing towards obstructive sleep apnea-hypopnea (OSAH). Nonetheless, currently, little is known about the effects of tongue muscle training (TMT) and threshold inspiratory muscle training (TIMT) on quality of life (QOL), physical activity and depression state. Therefore, aside from evaluating the impacts of OSAH on QOL, physical activity and depression, we would like to evaluate the effects of tongue muscle and inspiratory muscle training on QOL, physical activity and depression.
Methods: 61 moderate to severe OSAH participants were compared with 22 control participants on QOL, physical activity and depression state. In addition, OSAH participants were assigned to TMT, TIMT and CPAP group. Re-evaluations were performed after one month and three months post interventions.
Results: OSAH group was significantly lower in tongue protrusion strength (p〈0.05). Besides, the physical, psychological and the average QOL domain scores were significantly lower in OSAH (p〈0.05). Moreover, the total physical activity and total moderate activity performed were three-fold lower in OSAH group compared to the age- and BMI- matched control group. In addition, six-minute walk distance achieved by OSAH group was shorter in distance (p〈0.05). Physical and psychological domains were positively correlated to the six-minute walk distance while depression score was negatively correlated to all of the domains in WHOQOL (p〈0.001). Significant changes were found in AHI and sleep parameters after three months of TMT and TIMT training. After three months of TMT, TIMT and CPAP, significant improvements found over time in physical, psychological, social relationship, and the average QOL, as well as in the depression status and sleepiness level (p〈0.05). The physical activity showed no significant changes over time among the groups. However, six-minute walk distance increased over time in TIMT and CPAP groups.
Conclusion(s): Compared to the age- and BMI- matched control group, participants from the OSAH groups had lower QOL, physical activity, 6MWD and tongue protrusion strength that were impaired as a result of OSAH. However, three months of training with either tongue muscle training or threshold inspiratory training is compatible to the gold standard CPAP treatment in patients with moderate to severe OSAH.
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