Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane

碩士 === 國立中興大學 === 化學系所 === 104 === The Diels-Alder reaction is an efficient synthetic method to synthesize 6-members ring of the (-)-Oseltamivir framework. The synthetic method is separated into diene and dienophile. This thesis is introduced to prepare the diene fragment, 3-(buta-1,3-dien-1-yloxy)p...

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Main Authors: Hsien-Yang Huang Tseng, 黃曾絃揚
Other Authors: Tu-Hsin Yan
Format: Others
Language:zh-TW
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/54727481637178510388
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spelling ndltd-TW-104NCHU50650082017-02-11T16:10:04Z http://ndltd.ncl.edu.tw/handle/54727481637178510388 Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane 探討(-)-Oseltamivir片段:3-(buta-1,3-dien-1-yloxy)pentane之合成方法 Hsien-Yang Huang Tseng 黃曾絃揚 碩士 國立中興大學 化學系所 104 The Diels-Alder reaction is an efficient synthetic method to synthesize 6-members ring of the (-)-Oseltamivir framework. The synthetic method is separated into diene and dienophile. This thesis is introduced to prepare the diene fragment, 3-(buta-1,3-dien-1-yloxy)pentane, with cis-2-butene-1,4-diol 76, 2,5-dihydrofuran 79, propargyl alcohol 81, or pentan-3-yl formate 86 through nucleophilic substitution, E1, E1CB or Wittig reaction. Tu-Hsin Yan 楊圖信 2016 學位論文 ; thesis 98 zh-TW
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language zh-TW
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description 碩士 === 國立中興大學 === 化學系所 === 104 === The Diels-Alder reaction is an efficient synthetic method to synthesize 6-members ring of the (-)-Oseltamivir framework. The synthetic method is separated into diene and dienophile. This thesis is introduced to prepare the diene fragment, 3-(buta-1,3-dien-1-yloxy)pentane, with cis-2-butene-1,4-diol 76, 2,5-dihydrofuran 79, propargyl alcohol 81, or pentan-3-yl formate 86 through nucleophilic substitution, E1, E1CB or Wittig reaction.
author2 Tu-Hsin Yan
author_facet Tu-Hsin Yan
Hsien-Yang Huang Tseng
黃曾絃揚
author Hsien-Yang Huang Tseng
黃曾絃揚
spellingShingle Hsien-Yang Huang Tseng
黃曾絃揚
Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
author_sort Hsien-Yang Huang Tseng
title Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
title_short Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
title_full Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
title_fullStr Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
title_full_unstemmed Synthetic Studies toward the fragment of (-)-Oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
title_sort synthetic studies toward the fragment of (-)-oseltamivir:3-(buta-1,3-dien-1-yloxy)pentane
publishDate 2016
url http://ndltd.ncl.edu.tw/handle/54727481637178510388
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