| Summary: | 碩士 === 輔仁大學 === 物理學系碩士班 === 104 === In this thesis, we combined the surface plasmon resonance (SPR) based side-polished D-type optical fiber sensor with microfluidic chips to measure the refractive indices of different liquids. The D-type OFS is based on the Kretchmann’ s configuration. By using the optical fiber to guide the light source to the side-polished region with deposited gold film, surface evanescent wave excites the gold film to attain the SPR phenomenon. A CO2 laser scriber was used to ablate polymethylmethacrylate (PMMA) substrates for making the microfluidic chips. These chips are cheap and easy to be fabricated. We combined the microfluidic chip with the D-type optical fiber to measure the spectrum peak of liquids with different refractive indices. We changed a variety of refractive indices for observing the difference in the spectrum peak and calculate the corresponding sensitivity. In our experiments, four sets of samples were measured: 1.ethanol mixed with water; 2.methanol mixed with water; 3.ethanol and methanol mixed with water; 4.different concentrations of glucose solution. Liquids with different refractive indices were flowed into the microfluidic chip for observing their effects on the spectrum peak. The sensitivity of the present OFS was calculated to be in the order of 10-6 RIU. We believed that, in the future, this microfluidic chip-integrated OFS can serve as a biosensor to monitor subtle changes in biological samples such as blood glucose, allergen, and biomolecular interactions.
|
|---|
