Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes

碩士 === 中原大學 === 化學研究所 === 104 === The primary concern of this study is to explore the research on the development of an organocatalytic enantionselective Michael reaction of acetylacetone with β,β-disubstituted nitroalkenes. This reaction was catalyzed by a cinchona alkaloid-thiourea bifunctional or...

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Main Authors:	Hsuan-Hao Chang, 張軒豪
Other Authors:	Jeng-Liang Han
Format:	Others
Language:	zh-TW
Published:	2016
Online Access:	http://ndltd.ncl.edu.tw/handle/94590414878267456801

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spelling	ndltd-TW-104CYCU50650792017-08-27T04:30:11Z http://ndltd.ncl.edu.tw/handle/94590414878267456801 Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes 1,3-雙羧基化合物與 β, β-雙取代硝基烯烴之不對稱有機催化麥克加成反應 Hsuan-Hao Chang 張軒豪碩士中原大學化學研究所 104 The primary concern of this study is to explore the research on the development of an organocatalytic enantionselective Michael reaction of acetylacetone with β,β-disubstituted nitroalkenes. This reaction was catalyzed by a cinchona alkaloid-thiourea bifunctional organocatalyst, producing products in high yields (up to 98%) and enantioselectivites (up to 91% ee). This is the first example to construct β-amino derivatives bearing a synthetically valuable quaternary chiral center and a heterocyclic ring. Jeng-Liang Han 韓政良 2016 學位論文 ; thesis 276 zh-TW
collection	NDLTD
language	zh-TW
format	Others
sources	NDLTD
description	碩士 === 中原大學 === 化學研究所 === 104 === The primary concern of this study is to explore the research on the development of an organocatalytic enantionselective Michael reaction of acetylacetone with β,β-disubstituted nitroalkenes. This reaction was catalyzed by a cinchona alkaloid-thiourea bifunctional organocatalyst, producing products in high yields (up to 98%) and enantioselectivites (up to 91% ee). This is the first example to construct β-amino derivatives bearing a synthetically valuable quaternary chiral center and a heterocyclic ring.
author2	Jeng-Liang Han
author_facet	Jeng-Liang Han Hsuan-Hao Chang 張軒豪
author	Hsuan-Hao Chang 張軒豪
spellingShingle	Hsuan-Hao Chang 張軒豪 Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
author_sort	Hsuan-Hao Chang
title	Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
title_short	Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
title_full	Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
title_fullStr	Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
title_full_unstemmed	Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes
title_sort	organocatalytic enantioselective michael reaction of 1,3-dicarbonyl compounds with β, β-disubstituted nitroalkenes
publishDate	2016
url	http://ndltd.ncl.edu.tw/handle/94590414878267456801
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Organocatalytic Enantioselective Michael Reaction of 1,3-dicarbonyl compounds with β, β-Disubstituted Nitroalkenes

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