Development of Carbohydrate-based Primary Amine Organocatalysts and Application to Asymmetric Aldol Reaction of Cyclohexanone with Isatines.
碩士 === 中原大學 === 化學研究所 === 104 === In this work, six novel carbohydrate-based primary amine organo-catalysts bearing multiple hydrogen bonding donors were designed and sythesized for aldol reaction of cyclohexanone with isatines. Catalyst cat-5 catalyzed the asymmetric aldol reactions between isatin...
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| Format: | Others |
| Language: | zh-TW |
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2016
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| Online Access: | http://ndltd.ncl.edu.tw/handle/67294870744746691483 |
| Summary: | 碩士 === 中原大學 === 化學研究所 === 104 === In this work, six novel carbohydrate-based primary amine organo-catalysts bearing multiple hydrogen bonding donors were designed and sythesized for aldol reaction of cyclohexanone with isatines. Catalyst cat-5 catalyzed the asymmetric aldol reactions between isatin dervativers and cyclic ketons with good yields ( up to 89% ) and enantoselectivity ( up to 96% ).
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