Study of Application for Gynecological Disorders by Dang-Gui-Shao-Yao-San

• Main Authors: TU,SUZ-FAN, 杜思範
• Other Authors: LU,YU-LING
• Format: Others
• Language: zh-TW
• Published: 2016
• Online Access: http://ndltd.ncl.edu.tw/handle/88237199975500715400

碩士 === 嘉南藥理大學 === 藥學系 === 104 === Dang-Gui-Shao-Yao-San（DGSYS）is a widely used formula of traditional Chinese medicine（TCM）, it derived from “Jingui Yaolue,” a medical classic written by Zhongjing Zhang during the Eastern Han Dynasty. DGSYS has been used in gynecological disorders for thousands of years. It contains two groups of drug, one is a blood-activating ( Angelica ,White peony, Chuanxiong ), the other is stasis-eliminating drug(Hoelen, Bighead atractylodes, Alisma). The aim of this study is to explore DGSYS of clinical indications for gynecological disorders by National Health Insurance Research Database (NHIRD). We analysis medical records from 2005 to 2007 of NHIRD which treat gynecological disorders for women by DGSYS. The statistical analysis used SPSS/12.0 statistical software. The results of analysis present 11860 females used DGSYS from 2005 to 2007,which have clinical effect. The results show the highest utilization rate of DGSYS for the clinic are central Taiwan, and the administration age is mainly in the 11～50 years old female patients and treatment duration is 4～7 days. It usually was used in clinical to treat female’s dysmenorrheal, menstrual abnormalities, irregular menstrual cycles, no menstruation, vaginal discharge and many other gynecological disorders. So, we predict that DGSYS is important in female’s physiological uncomfortable period. It could reduce gynecological disorders, such as menstruation, leucorrhea, pregnancy and childbirth. In fact, The patients using DGSYS to treat dysmenorrhea comparing than unused TCM patients has lower incidence of endometriosis (5.30% vs. 8.57%). The modern medicals indicate DGSYS have anti-inflammatory; analgesic; inhibit uterine smooth muscle contraction and regulate both the hypothalamus - ovarian function. Activating blood stasis method in Traditional Chinese Medicine（TCM） also has same treatment of dysmenorrhea or endometriosis. Therefore, the DGSYS was used to women for long-term Conditioning is feasible. However, DGSYS therapeutic effectiveness and safety evaluation analysis was not provided in this study. Further well-designed, randomized, double-blinded and placebo-controlled clinical trials are still needed to elucidate this problem in the future.