| Summary: | 碩士 === 長榮大學 === 生物科技學系(所) === 104 === Tissue engineering has been treated as a preferred method of treatment for reconstructing defective tissues in various biomedical engineering applications. Nerve cells at an injury site have to be guided in the appropriate direction to accelerate nerve regeneration. Chitosan was used as materials due to its good biocompatibility. Carbon nanotubes (CNTs) are an ideal reinforcing material due to their nanometer size, their extraordinary mechanical strength and high electrical conductivity. Gelatin is a biodegradable polymer with excellent biocompatibility, plasticity, and inexpensive and much easier to obtain. Compared with traditional crosslinking agents, genipin has less cytotoxicity and better biocompatibility. Incorporation of far-irradiation ray into a nerve conduit hope to improve peripheral nerve regeneration. The genipin cross-linked gelatin annexed with CNTs/chitosan as a nerve guide materials are produced. The far-infrared ray irradiation can increase the cell activity. We hope this composite has a good biocompatibility which is necessary for clinical usage. Through integration of far-irradiation ray and biomaterials, we hope to establish a new perspective of research.
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