Drug Utilization and Treatment Analysis on Herpes Zoster: A Study based on National Health Insurance Database

• Main Authors: Min-Hui Tseng, 曾敏惠
• Other Authors: Prof. Chin-Yin Huang.
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/66308564133583294094

碩士 === 東海大學 === 工業工程與經營資訊學系 === 103 === Chickenpox, also known as varicella, is a virus that infects a man in the childhood. Once the chickenpox is healed, the chickenpox virus is lurking in the dorsal root ganglia. As the man’s body immune system is weak because of aging, illness or on stress, chickenpox virus will be re-activated and transferred to dermatomes through dorsal roots; and caused a neuropathic pain and herpes. It usually named shingle or herpes zoster. The objectives of this research is to utilize the National Health Insurance Database (NHIRD) to investigate (1) the demographics of the patients with herpes zoster, (2) drug utilizations of the patients with herpes zoster and with post-herpetic neuralgia, and (3) correspondence of the current Chinese medicine utilization with the suggestions in the ancient Pharmacopoeia. This research retrieved 1208 patients with ICD-9-CM codes of 053.11, 053.19, 053.20, 053.21, or 053.9 from 300,000 patients randomly sampled from the 2010 NHIRD. The patients are stratified by (1) western, Chinese, or hybrid institutions, (2) level of hospitals, and (3) with or without post-herpetic neuralgia (ICD-9-M 053.19). The above strata were evaluated by Chi square or ANOVA tests. The results of the research indicate that there is no significant association between gender and post-herpetic neuralgia. Clinics are the most popular institutions for patient visitations. The number of patients increases as the patients age for with herpes zoster or with post-herpetic neuralgia. For drug utilization, antipyretic analgesics, antibiotics, and steroid were the major medicines. For patients who choose Chinese medicine to cure the disease, Chin-Lar-Li-She and Jie-Du-Jhih-Tong are the most popular ones.