Effects of thin film metallic glass coating on skin grafting using a dermatome blade

• Main Authors: Yong-Jhe Tseng, 曾永?
• Other Authors: Jinn P. Chu
• Format: Others
• Language: en_US
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/75506806799669046613

碩士 === 國立臺灣科技大學 === 材料科學與工程系 === 103 === Skin grafting is usually used to treat extensive wounding, scald, severe skin loss area and specific surgeries, which require for skin healing. A dermatome blade is typically used for skin grafting and then to obtain a good quality of dermatome blade is necessary. Based on previous research in our group, the wound surface roughness is found to be influenced by the sharpness and durability of dermatome blade. As a result, the sharper blade is expected to help reduce skin damages and accelerate the wound healing. Coating is one of promising approaches to enhance the sharpness and durability of dermatome blades. Thin film metallic glasses (TFMGs) would be a good candidate for enhancing the surgical performance of dermatome due to their excellent mechanical properties. In this study, 200nm-thick Zr-based, W-based and Fe-based TFMGs are deposited on dermatome blades by using magnetron sputtering. The wear resistance and sharpness of the dermatome blade are found to be enhanced after coating. It is suggested that the unique properties of TFMG such as high strength, good wear-resistances play roles in protecting dermatome blade during animal test. However, there is no obvious reduction of surface roughness examined on TFMG-coated dermatome blade. In addition, compared with the bare dermatome blade, wound healing and biopsy morphology, performed by the TFMG-coated one, exhibit no apparent improvements. This result might be attributed to the inhomogeneous nature of animal as well as the healthy condition of animal.