The inhibitory mechanisms of β-lapachone on cisplatin-induced damages in fibroblast

The inhibitory mechanisms of β-lapachone on cisplatin-induced damages in fibroblast

碩士 === 國立臺灣大學 === 解剖學暨細胞生物學研究所 === 103 === DNA-damaging agents can be used as chemotherapeutic drugs,which have a long history in clinical use. Cisplatin (CDDP) is categorized as the most popular and the first line chemotherapeutic drug. It has a platinum core with two chloride leaving groups and...

Full description

Bibliographic Details
Main Authors:	Yu-Ting Lo, 羅于庭
Other Authors:	Hsiu-Ni Kung
Format:	Others
Language:	zh-TW
Published:	2015
Online Access:	http://ndltd.ncl.edu.tw/handle/qvd6gn

Similar Items

The Inhibitory Effects of β-Lapachone on the Inflammation-Induced Fibrosis
by: Wei-Hsin Peng, et al.
Published: (2015)

Synthesis of new aldehyde derivatives from β-lapachone and nor-β-lapachone
by: Milton N. da Silva, et al.
Published: (2003-08-01)

KL1333, a derivative of β-lapachone, protects against cisplatin-induced ototoxicity in mouse cochlear cultures
by: Han-Sol Lee, et al.
Published: (2020-06-01)

β-lapachone Induces Human Hepatoma Cell Death
by: Lai, Chyuan-Jing, et al.
Published: (1995)

Characterization of the effects of β-Lapachone on zebrafish embryonic development
by: Yi-Ting Wu, et al.
Published: (2008)

Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
by: Danielly C. Ferraz da Costa, et al.
Published: (2020-02-01)

The Role of β-Lapachone induced endothelial cells death and anti-angiogenesis
by: Chiao-Wen Lin, et al.
Published: (2006)

The Cytotoxicity of β-Lapachone on Human Osteosarcoma Cell Line
by: Sheng-Yi Lin, et al.
Published: (2001)

β Lapachone blocks the cell cycle and induces apoptosis in canine osteosarcoma cells
by: Vanessa S. Cruz, et al.

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation
by: Wenxiu Zhao, et al.
Published: (2021-10-01)

Mechanism of beta-lapachone-induced apoptosis in human prostate cancer cells
by: Cheng-Chi Chang, et al.
Published: (2000)

Studies of antagonistic mechanisms of LPS-induced inflammatory response by betta-lapachone
by: Tzeng, Huei-Ping, et al.
Published: (1998)

Effects of β-Lapachone on the proliferation and migration in 3T3 cells
by: Mei-Jun Yang, et al.
Published: (2006)

β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos
by: Huang Chang-Jen, et al.
Published: (2011-09-01)

The Role of NO (Nitric Oxide) in the Mechanism of beta-Lapachone-Induced Endothelial Cell Death
by: Hsiu-ni Kung, et al.
Published: (2003)

Investigating the Apoptotic Mechanism Induced by beta-Lapachone on Human Endothelial Cells under
by: Tsung-Hao Liu, et al.
Published: (2004)

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.
by: Juliana M C Barbosa, et al.
Published: (2021-01-01)

Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and β-lapachone combination treatment
by: Brown Jayann, et al.
Published: (2004-08-01)

Mechanically Robust Gastroretentive Drug-Delivery Systems Capable of Controlling Dissolution Behaviors of Coground β-Lapachone
by: Hyeongmin Kim, et al.
Published: (2019-06-01)

β-Lapachone Increases Survival of Septic Mice by Regulating Inflammatory and Oxidative Response
by: Ana L. de B. Oliveira, et al.
Published: (2020-01-01)

β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway.
by: Ji-Ye Kee, et al.
Published: (2017-01-01)

Temperature-Sensitive Gels for Intratumoral Delivery of β-Lapachone: Effect of Cyclodextrins and Ethanol
by: Marcilio S. S. Cunha-Filho, et al.
Published: (2012-01-01)

Effects of beta-lapachone on wound healing
by: Hsiu-Ni Kung, et al.
Published: (2008)

The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1
by: Hollie E. Flick, et al.
Published: (2013-01-01)

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone
by: Laura Torrente, et al.
Published: (2020-02-01)

β-Lapachone ameliorates lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.
by: Moon Hee Jeong, et al.
Published: (2014-01-01)

ANTHELMINTIC ACTIVITY OF LAPACHOL, β-LAPACHONE AND ITS DERIVATIVES AGAINST Toxocara canis LARVAE
by: Taís MATA-SANTOS, et al.
Published: (2015-06-01)

Terpinen-4-ol, tyrosol, and β-lapachone as potential antifungals against dimorphic fungi
by: Raimunda Sâmia Nogueira Brilhante, et al.

The mechanism of inhibitory effects of low molecular weight fucoidan on γ-radiation and TGF-β1 induced fibrosis
by: Chen, Yu-Ting, et al.
Published: (2018)

Exploring the Effect of Beta-Lapachone on Cardiomyocytes in Oxidative Stress.
by: Yu-Mei Shin, et al.
Published: (2011)

Synthesis and Biological Evaluation of beta-Lapachone Derivatives.
by: Shin-I Peng, et al.
Published: (2011)

NQO1 is Required for β-Lapachone-Mediated Downregulation of Breast-Cancer Stem-Cell Activity
by: Dong Wook Kim, et al.
Published: (2018-11-01)

Cytotoxicity assessment of beta-lapachone in endothelial cells
by: Patrícia de Almeida Machado Gonçalves, et al.
Published: (2021-04-01)

β-LAPachone is renoprotective in streptozotocin-induced diabetic mice via regulating the PI3K/Akt/mTOR signaling pathway
by: Davoud Sanajou, et al.
Published: (2021-05-01)

Inhibitory Effect of Zacopride on Cisplatin-Induced Delayed Emesis in Ferrets
by: Yamakuni Hisashi, et al.
Published: (2006-01-01)

Sulindac and its Metabolites Enhance NQO1-dependent Cytotoxicity on Human Lung Cancer Cells by β-Lapachone
by: Tsai-Yun Weng, et al.
Published: (2009)

β-lapachone suppresses tumour progression by inhibiting epithelial-to-mesenchymal transition in NQO1-positive breast cancers
by: Yang Yang, et al.
Published: (2017-06-01)

Effects of a novel β–lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis
by: Danielle Oliveira dos Anjos, et al.
Published: (2016-12-01)

Upregulation of NAD(P)H:Quinone Oxidoreductase By Radiation Potentiates the Effect of Bioreductive β-Lapachone on Cancer Cells
by: Eun K. Choi, et al.
Published: (2007-08-01)

Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by β-lapachone treatment.
by: Hyemi Lee, et al.
Published: (2011-01-01)