| Summary: | 碩士 === 國立臺灣大學 === 光電工程學研究所 === 103 === Continuous ocular dimensional profile, intraocular pressure (IOP), has been known as an important diagnostic method for patients to measure glaucoma over 24hours, nocturnally and diurnally, as well as the number of peaks and troughs diurnally and nocturnally. Consequently, continuous IOP monitoring is required for adjusting the dosage and frequency of anti-glaucomatous agents for each individual.
In this work, a fully passive, non-invasive optical device is proposed for continuous IOP monitoring. The device is composed of a contact lens sensor with double-layered structure which utilizes moiré fringe to characterize the variation of the cornea curvature. Unprecedentedly our device is able to reach 1 mmHg sensitivity over a wide range of 20 mmHg at an increase of spatial period to from the resultant moiré fringe. Compared to other contact lens-based sensors, our device is simple, passive, no imbedded electric circuit, and capable for monitoring the IOP variability of glaucoma patients.
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