| Summary: | 博士 === 國立臺灣大學 === 生醫電子與資訊學研究所 === 103 === Myofascial pain syndrome (MPS) is a common pain issue that disturbs many people. The MPS not only causes the painful condition but affects the patient’s mood state and even life function. There have been many studies show variety of treatment approaches including invasive and noninvasive. However the efficiency of noninvasive therapies has its limitation.
Application of bio-resonance wave (BRW) with microcurrent electrical nerve stimulator (MENS) may work on respective cells by means of charged molecule polarization into both electric potential and resonant action potential in order to open the electric gate channel of gap junction intercellular communication. An integration effect of neighboring cells may form semiconductor-like tissue block and cellular changes of cytoskeleton and morphology conformity.
This study wants to discuss whether the bioresonance therapy is considered as a new treatment to myofascial pain syndrome. The BRW electric field energy of applied wave frequency and cycle frequency (WF/CF Hz) included an 8min easing phase of 25,000 ~500 /100 along with an 8min healing phase of 500 ~10 /10. The applied BRW energy was of assorted WF bank including single frequency, sweep decreasing, and spread contraction with same monophasic positive square waves of 50% wave duty (WD) based on same specifications of 600uA current at 6.2V mean peak potential despite of different cycle duty (CD) in test group (C1) 70% and in control group (C2) 1%.
With 0.24W BRW energy of single frequency combinations (WF Hz /CD %), the MCF-7 cell line with 2/70 energy showed better cellular morphology conformity of round-up discrete cell and homogeneous grouped cells based on statistics morphology data among four applied energy combinations of 2/50, 2k/50, 2/70, and 2k/70. With the stated treatment of BRW energy, the ICF-like buffer system showed better oxidative tolerance under H2O2 challenges based on trend difference of oxidation reduction potential (ORP) data. The MLE-15 cell line with stated treatment and with added 30min of 100uM H2O2 challenge showed better physiological metabolism based on likely differences of increased oxygen consumption rate (OCR) and decreased extra cellular acidification rate (ECAR) from extracellular flux analyzer XF-24.
Sixty patients with MPS were divided into two groups: bioresonance group and control group. After twelve times interventions, the bioresonance group shows significant decreases in VRS, NDI, SF-12 and PPT, while the control group only shows significant decreases in PPT. This study suggests that bioresonance therapy might be considered as a new intervention to myofascial pain syndrome.
Key words: Myofascial Pain Syndrome, Bio-resonance electric field wave, Trigger Point, Muscle Spindle Hypothesis, In Vivo Resonance.
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