Medication adherence of Statins and Healthcare Utilization among the Middle-aged and Elderly with Coronary Heart Disease：A Cohort study in Taiwan

• Main Authors: Wei-Ling Huang, 黃韋綾
• Other Authors: Ying-Chun Li, Ph. D
• Format: Others
• Language: zh-TW
• Published: 2015
• Online Access: http://ndltd.ncl.edu.tw/handle/3gxqu5

碩士 === 國立中山大學 === 企業管理學系醫務管理碩士班 === 103 === Objective： The purpose of this study is to explore the relationship of patients’ medication adherence with the statins therapy and inpatient visit the in Taiwan. Methods： A corhort study was implemented to use the National Health Insurance Research Database（NHIRD）between January 2001 and December 2007, to analysis the patient who had taken the medicine of statins at the first time and never had diagnosis of coronary heart disease（CHD）. The patient were followed until occurred first inpatient visit with coronary heart disease or end of study period（Dec. 31 2007）. The medication adherence was calculated as medication possession ratio（MPR）which was sum of days of supply of the statins medications divided by follow-up duration. Result： In the analyzed of 19371 patients who use statins therapy, 11642 patients（59.17%）had high medication adherence（MPR≧80％）and the rest patients（40.83%）had been included in low medication adherence（MPR＜80％）. There were significantly higher adherence for patients were male, elderly, CCI=1, in medical center and in rural area. The hospitalized risk increased with MPR<80 %, male, elderly, and more comorbidities. The hospitalization costs showed comorbidities with MPR<80 %, male, elderly, more comorbidities, patient in medical center, teaching-hoapital and suburban. Conclution： Lipid-lowering therapy, statins medication is well known to reduce cardiovascular risk across a wide range of patients. It is very important to follow-up and compliance with statins therapy. This study finded that good adherence to statin treatment was associated with lower risk of occurred CHD.