| Summary: | 碩士 === 國立澎湖科技大學 === 食品科學研究所 === 103 === Abstract
“Garbo” watermelon is one of specie (watermelon) cultivated in Penghu county. The objectives of this study were use the watermelon to develop higher economic value functional product. In this study, to selected higher citrulline extracts, different extract methods, different parts of watermelon fruit, and different species were examined the citrulline concentrations of watermelon. The high citrulline extracts of watermelon were produced. Further,assess antioxidant ability,anti-inflammatory assay,protect cardiomyocytes apoptosis effects. of citrulline extracts of watermelon by in vitro assay.
The results shown antioxidant activities of citrullin extract by 6M HCl was higher than water extraction and the antioxidant capacity of watermelon different parts were peel＞ pulp＞ White. For immunoassay, the results showed citrulline and Garbo melon extract were slow down the amount of LPS-induced generation of NO and myocardial cells have the same phenomenon. For TNF-a assay, TNF-a content were increased by citrulline and Garbo melon extract treatments and have dose-drpendent. For LDH assay, The results show that Garbo melon extract and citrulline can reduced the damage caused by H2O2 in myocardial cells.
In cardiac apoptosis, apotosis were showed slowly by citrulline and “Garbo” watermelon extract treatment. The results of this study will provide useful information to developing the special agricultural products
Key world：Citrulline、Citrullus lanatus、Antioxidant、anti-inflammatory
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