PPL2ab neurons modulate sexual responses in Drosophila females through dopamine.
碩士 === 國立暨南國際大學 === 應用化學系 === 103 === Dopamine (DA), is a kind of neurotransmitter that widely distributed in brain and central nervous system. DA plays an important role in many physiological response, including sleep, activity, learning or sexual activities. Previous studies found that PPL2ab ne...
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| Format: | Others |
| Language: | zh-TW |
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2015
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| Online Access: | http://ndltd.ncl.edu.tw/handle/58733437371517587752 |
| Summary: | 碩士 === 國立暨南國際大學 === 應用化學系 === 103 === Dopamine (DA), is a kind of neurotransmitter that widely distributed in brain and central nervous system. DA plays an important role in many physiological response, including sleep, activity, learning or sexual activities. Previous studies found that PPL2ab neurons in male Drosophila control courtship intensity by regulating DA, that can even induce homosexual courtship behavior in male flies. This study will further analyze whether PPL2ab neurons are also involved in female sexual responses. We find that keeping homeostasis of DA level in a subset of cells in the PPL2ab neuronal cluster is necessary for maintained the female receptivity. These results may provide the foundation for deciphering the circuitry involved in sexual motivation in the female Drosophila brain.
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